An Open-Label Extension Study of Voxelotor Administered Orally to Pediatric Participants With Sickle Cell Disease Who Have Participated in Voxelotor Clinical Trials

Locations

7 United States sites

3 United Kingdom sites

2 Lebanon sites

Age

4 to 18 Years

Phase

Phase 3

Study type

Interventional

Gender

All

Interventions

Drug

Compensation

Unknown

About the study

Open-label extension study of voxelotor for pediatric participants ages 4 to 18 years old
with Sickle Cell Disease who have participated in voxelotor clinical trials.

participation requirements

– Male or female participant with SCD, aged ≥ 4 to ≤ 18 years, who participated and
received study drug in a GBT-sponsored voxelotor pediatric clinical study

– Participant has provided written assent (both the consent of the participant’s legal
representative or legal guardian and the participant’s assent [where applicable] must
be obtained)

participation restrictions

– Female participant who is breastfeeding or pregnant

– Participant withdrew consent from a GBT-sponsored voxelotor pediatric clinical study

Locations

  • Washington, District of Columbia, United States, Children's National Medical Center, 20010
  • Atlanta, Georgia, United States, Children's Healthcare of Atlanta, 30342
  • Chicago, Illinois, United States, Ann and Robert Lurie Children's Hospital of Chicago, 60611
  • Baton Rouge, Louisiana, United States, Our Lady of the Lake Regional Medical Center, 70808
  • Kansas City, Missouri, United States, Children's Mercy Hospital Kansas City, 64108
  • Pittsburgh, Pennsylvania, United States, Children's Hospital of Pittsburgh of UPMC - Blood and Marrow Transplantation (BMT) and Cellular Therapies, 15224
  • Memphis, Tennessee, United States, St. Jude Children's Research Hospital (SJCRH), 38105
  • Beirut, Lebanon, American University of Beirut Medical Center (AUBMC), 1107-2020
  • Tripoli, Lebanon, Nini Hospital, 1300
  • London, United Kingdom, Royal London Hospital, Barts Health NHS Trust, E1 1BB
  • London, United Kingdom, University College London Hospitals NHS Foundation Trust, NW1 2PG
  • London, United Kingdom, Evelina London Children's Hospital - Guy's and St. Thomas' NHS Foundation Trust, SE1 7EH

More info

View on ClinicalTrials.gov
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