Association Between Low Bone Density, Vertebral Fractures, and Pain in Sickle Cell Disease

About the study

A prospective study to determine how low bone mineral density and/or vertebral compression fractures associate with pain in adults with sickle cell disease

Study point of contact

Oyebimpe O Adesina, MD, MS
[email protected]
Edward Lingayo
[email protected]


18 Years - 80 Years

Study type




participation requirements

Age 18-80 years with SCD (any genotype, confirmed by hemoglobin electrophoresis or high performance liquid chromatography)
Ability to provide written informed consent
Ability to lay on a DXA scanner
Negative urine pregnancy test for women of childbearing potential at study entry

participation restrictions

Pregnant women
Adults unable to consent
Individuals who are not yet adults (infants, children, teenagers)
Hospitalizations (any cause) within 2 weeks of study entry

Last updated 2022-11-03