Cardiovascular Complications of Sickle Cell Disease

Study point of contact

Amit R Patel, M.D.
773-702-1843
[email protected]

Locations

1 United States site

Age

> 18 Years

Study type

Observational

Gender

All

Interventions

Procedure

Compensation

Unknown

About the study

In this research study, we are using heart imaging exams and blood testing, in order to gain
an improved understanding of the pulmonary (lung) hypertension and cardiovascular (heart)
complications that often occur in sickle cell patients. Information gathered from the healthy
volunteers that participate in this study will be compared to information from the sickle
cell patients in this study in order to help further our understanding.

participation requirements

– Patients must be 18+

– Patients who were diagnosed with SCD confirmed by high-pressure liquid chromatography
or hemoglobin electrophoresis will be eligible for the study

– Only patients in stable condition will be included

– Patients receiving transfusions will not be excluded

participation restrictions

– Patients with vaso-occlusive crises or an episode of acute chest syndrome within the
previous four weeks (after 4 weeks have passed, the patients may be re-evaluated for
eligibility)

– Patients with high degree heart block; active, hemodynamically significant,
ventricular arrhythmias; unstable coronary syndromes; history of myocardial infarction
within 1 month of the study.

– Contraindications to gadolinium-enhanced magnetic resonance examination such as severe
claustrophobia, Pacemaker, defibrillators, cerebral aneurysm clips, or
neurostimulator.

– Pregnancy

– Patients with sinus node dysfunction

Locations

  • Chicago, Illinois, United States, University of Chicago Medical Center, 60430 [Recruiting]