Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell Via Mobile Applications

About the study

The investigators are conducting a comparative effectiveness trial among adult patients with sickle cell disease (SCD) who report chronic pain (N = 350), randomized to receive either mobile phone-delivered computerized cognitive behavioral therapy (cCBT; n = 175) or digital education (m-Education; n = 175). Both intervention groups will receive weekly (more frequent if requested or needed) follow-up with a health coach for at least 3 months to reinforce learned materials. Both groups will also use their mobile device to track daily pain, mood, and medication used for two-week periods at baseline and each of the follow-up points (3, 6 and 12 months). Participants will also be given access to a study-associated online support group page where members can discuss with other patients, issues participants faced and what skills were or could be used to address them. Participants will continue all routine care including opioid pain management and novel therapies.

Study point of contact

Laura De Castro, MD
412-648-6575
[email protected]
Charles Jonassaint, PhD
412-586-9850
[email protected]

Locations

5 United States sites

Age

> 18 Years

Phase

Not Applicable

Study type

Interventional

Gender

All

Interventions

Other

Compensation

Unknown

participation requirements

People with any type of sickle cell disease
Male or female, age 18 years or older
Reports chronic pain: i.e pain more days that not for the past 3 months or longer and/or is prescribed daily or long-acting opioids for pain.
English speaking

participation restrictions

Any potential participants who fail consent comprehension questions

Locations

  • Chicago, Illinois, United States, University of Illinous-Chicago, 60607 [Recruiting]
  • Baltimore, Maryland, United States, Johns Hopkins, 21287 [Recruiting]
  • Durham, North Carolina, United States, Duke University, 27708 [Recruiting]
  • Columbus, Ohio, United States, Ohio State University, 43210 [Recruiting]
  • Pittsburgh, Pennsylvania, United States, University of Pittsburgh, 15213 [Recruiting]
Last updated 2021-10-04