Effects of Prebiotics on Gut Microbiome in Patients Undergoing Stem Cell Transplants

About the study

The purpose of this study is to see whether hematopoietic stem cell transplant (HSCT) patients can consistently eat a diet rich in prebiotics. This type of diet may be helpful in maintaining diversity in the gastrointestinal (GI) system and therefore potentially decreasing risk of other GI problems.

Study point of contact

Taylor Durham
434 243 4281
[email protected]
Danyelle Coley
(434) 982-5027
[email protected]

Locations

1 United States site

Age

> 18 Years

Phase

Not Applicable

Study type

Interventional

Age

18 Years -

Gender

All

Interventions

Other

Compensation

Unknown

participation requirements

Agreement to adhere to Lifestyle Considerations(prebiotic diet) throughout study duration
Adults (≥18 yrs of age)
Able to provide informed consent
Are willing/able to incorporate the required foods in their diet

Eligible, suitable and planning to undergo a stem cell transplant:

Either allogeneic or autologous
With any conditioning regimen (e.g. both myeloablative and reduced intensity conditioning)
Matched related, matched unrelated, haplo-identical and cord blood transplants will be included.

participation restrictions

Patients undergoing a second allogeneic or autologous transplant or an allogeneic transplant after an autologous transplant.
Anticipation of requirement of broad spectrum antibiotics 1 week prior to admission for HSCT (through HSCT)
Patients with any prior history of C.Diff infection

Locations

  • Charlottesville, Virginia, United States, University of Virginia, 22903 [Recruiting]
Last updated 2022-02-14