Effects of Prebiotics on Gut Microbiome in Patients Undergoing Stem Cell Transplants

Study point of contact

Danyelle Coley
(434) 982-5027
[email protected]
Gianna Strand
434 243 6377
[email protected]

Locations

1 United States site

Age

> 18 Years

Phase

N/A

Study type

Interventional

Gender

All

Interventions

Other

Compensation

Unknown

About the study

The purpose of this study is to see whether hematopoietic stem cell transplant (HSCT)
patients can consistently eat a diet rich in prebiotics. This type of diet may be helpful in
maintaining diversity in the gastrointestinal (GI) system and therefore potentially
decreasing risk of other GI problems.

participation requirements

1. Agreement to adhere to Lifestyle Considerations(prebiotic diet) throughout study
duration

2. Adults (≥18 yrs of age)

3. Able to provide informed consent

4. Are willing/able to incorporate the required foods in their diet

5. Eligible, suitable and planning to undergo a stem cell transplant:

1. Either allogeneic or autologous

2. With any conditioning regimen (e.g. both myeloablative and reduced intensity
conditioning)

3. Matched related, matched unrelated, haplo-identical and cord blood transplants
will be included.

participation restrictions

1. Patients undergoing a second allogeneic or autologous transplant or an allogeneic
transplant after an autologous transplant.

2. Anticipation of requirement of broad spectrum antibiotics 1 week prior to admission
for HSCT (through HSCT)

3. Patients with any prior history of C.Diff infection

Locations

  • Charlottesville, Virginia, United States, University of Virginia, 22903 [Recruiting]
Last updated 2021-03-17 Enroll Now