Evaluation of Left Ventricular Function by Speckle Tracking Echocardiography in Patient Hospitalised in Intensive Care Unit for Vaso-occlusive Crisis

Study point of contact

Xavier Monnet, MD, PhD
00331 45 21 35 39
[email protected]

Locations

1 France site

Age

> 18 Years

Study type

Observational

Gender

All

Interventions

Other

Compensation

Unknown

About the study

Vaso-occlusive crisis in Sickle cell disease might alter myocardial function through micro
vascular obstruction. Evaluation of strain alteration using speckle tracking echocardiography
is a non invasive technique that may allow us to observe such myocardial dysfunction. No such
study has yet been conducted in patient hospitalised in intensive care unit. Our hypothesis
is that strain alteration during vaso-occlusive crisis, if they do exist, can be correlated
with other markers of myocardial injury such as troponin level or thoracic pain.

participation requirements

– Hospitalisation in an intensive care unit for vaso-occlusive crisis

participation restrictions

– Pregnancy

– Individuals under guardianship

– Unsufficient echogenicity

– Thoracic pain prohibiting echocardiography assessment

Locations

  • Le Kremlin-BicĂȘtre, France, Medical Intensive Care Unit [Recruiting]