|Megan Connolly, PhD|
1 United States site
8 to 17 Years
– Children and adolescents with SCD (HbSS, HbSC, HbS-beta0 thalassemia, or HbS-beta+
thalassemia) between the ages of 8 and 17 years old with pain-related disability and
who are currently prescribed short- or long-acting opioid medications.
1. Participants will meet at least one of the following criteria for pain-related
disability: 1) Have had at least 3 pain crises in the last year, 2) Have had at
least one admission for pain in the last year, or 3) Have missed at least one
week of school (5 days) in the last year
2. Current prescription of opioids will be confirmed by participants’ primary
hematologist, review of the electronic medical record, and discussion with the
– Patients and caregivers with limited English proficiency, a neurodevelopmental delay,
or a visual or motor impairment that would interfere with their ability to complete
the assessments and intervention.
– Documented history of major depressive disorder in medical record and/or through
discussion with their primary hematology suggesting that patients may need a specific
and higher level of therapeutic care.
– Patients have regularly scheduled outpatient therapy sessions outside of the study.