| Fenella Kirkham, Dr | |
| [email protected] |
2 United Kingdom sites
4 to 16 Years
SS
Phase 2
Interventional
All
Device
Unknown
The hypothesis is that in sickle cell anaemia, nocturnal oxyhaemoglobin desaturation, is
associated with low processing speed index, and this morbidity can be reduced with overnight
auto Continuous Positive Airways Pressure and/or oxygen supplementation.
1. Age >4 years.
2. Informed consent with assent in accordance with UK ethical committee(COREC) system
must be signed by the patient’s parent or legally authorized guardian acknowledging
written consent to join the study. When suitable, patients will be requested to give
their assent to join the study.
3. Haemoglobin SS (homozygous sickle cell anaemia) diagnosed by standard techniques.
Participating institutions must submit documentation of the diagnostic haemoglobin
analysis.