The Feasibility of the PAINReportIt Guided Relaxation Intervention for Pain and Stress in Adult Inpatients With Sickle Cell Disease


1 United States site


> 18 Years



Study type








About the study

The goal of this research study is to improve the self-management of pain, stress, and
cognitive/affective symptoms that may result in adult inpatients with sickle cell disease
(SCD) by determining the feasibility of a self-management guided relaxation (GR) stress
reduction intervention using a tablet-based mobile device. Currently, opioid analgesics are
primarily used to treat SCD pain while self-managed behavioral modalities such as GR, are
rarely used, particularly, in inpatient settings. Little is known about the effects or
mechanisms of GR on pain, stress, and cognitive/affective symptoms in adults with SCD
hospitalized with pain. Emerging evidence from the hypothalamic pituitary adrenal (HPA) axis
theory offer insights for understanding the mechanisms. Adding GR as a supplement to
analgesic therapies will address the dearth of self-management strategies for controlling
pain in SCD. GR is a simple and cost-effective non-drug intervention that could reduce pain
and stress in inpatients with SCD. GR is an intervention where inpatients with SCD are
directed to listen to and view audio-visual recordings while they visualize themselves being
immersed in that scenario.

participation requirements

– Has SCD diagnosis;

– Reports pain 3 or greater in the previous 24 hours (0-10 scale)

– admitted to University of Florida (UF) Health for pain crisis

– Speaks and reads English

– 18 years of age or older

– self-identifies as being of African descent or Hispanic

participation restrictions

– Legally blind

– Physically or cognitively unable to complete study measures


  • Gainesville, Florida, United States, University of Florida, 32610