The study will use web-based data collection (SCKnowIQ) and intervention delivery strategies enhanced by nudges and tailored boosters in a sample of 430 adult men and women, aged 18-35 yr with SCD or SCT, at-risk, and planning within 2 years to have a child free of SCD.
18 Years - 35 Years
Diagnosis of SCD (HbSS, HbSC, HbS-beta-0 thalassemia, and HbS-beta+ thalassemia) or report of SCT (both SCD/ SCT is Hgb electrophoresis confirmed);
Able and intends to conceive a child in the next 2 years (first child or another child);
Speaks and reads English;
18 to 35 years;
At-risk for having a child with SCD (i.e., sexual/ reproductive partner has SCD, SCT, or unknown sickle cell status); and
Wants to avoid the risk of a child with SCD.
The age range is based on typical reproductive age for SCD where median survival is 42 years for men and 48 years for women.
Physically unable to complete the study questionnaires or the intervention;
Report health history of hysterectomy, tubal ligation, medically or surgically induced menopause, or vasectomy that would
Prevent ability to bear children;
Report a desire to remain childless or have no further children;
Report knowing or being a relative or friend of a participant previously enrolled in the study, or
Previous participation in a CHOICES study.