Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia

About the study

The investigators will attempt to develop a more accurate equation to estimate eGFR in
pediatric and adult sickle cell patients

Study point of contact

Jeffrey Lebensburger, DO, MSPH
205 638-9285
[email protected]

Locations

4 United States sites

Age

5 to 50 Years

Genotypes

SCA, HbSS

Study type

Observational

Gender

All

Interventions

Diagnostic Test

Compensation

Unknown

participation requirements

– SCA patients (HbSS and SB0 thalassemia)

– Age: 5.0-50.0 at enrollment

participation restrictions

– Recent SCA complication associated with hospitalization (within 30 days) or ED visit
(within 14 days)

– Current AKI defined as >0.3mg/g increase in SCr from prior visit

– Known history of anaphylaxis with contrast agent or known pregnancy

Locations

  • Birmingham, Alabama, United States, University of Alabama at Birmingham, 35223 [Recruiting]
  • Chicago, Illinois, United States, University of Illinois Chicage, 60612 [Not yet recruiting]
  • Memphis, Tennessee, United States, St Jude Childrens Research Hospital, 38106 [Not yet recruiting]
  • Memphis, Tennessee, United States, University of Tennessee Health Science Center, 38163 [Not yet recruiting]
Last updated 2021-04-09