CaRISMA
To identify treatments that do not rely only on opioids or other medications. Participants will use their smartphone to answer questionnaires and interact with a mobile application.
1 United States site
18 years and older
All SCD
Digital
Sickle Cell and the COVID-19 Vaccine
Sickle Cell 101 is conducting a study on the attitudes and impacts of the COVID-19 vaccine in the sickle cell community.
1 Global site
All
All genotypes
Online survey
Venous Thrombosis Biomarkers in SCD and SCT
To study blood clotting in SCD because it is the most common cause of vascular death after a heart attack or stroke.
1 United States site
18 to 80 Years
All SCD, SCT
Observational
13 Apr 2021
Treatment with oral Oxbryta (voxelotor) leads to rapid and sustained rises in hemoglobin levels, reduces red blood cell destruction (hemolysis), and improves overall health in adolescents and adults with sickle cell disease (SCD), according to full, nearly 1.5-year data from the Phase 3 HOPE clinical trial.
08 Apr 2021
A higher 600 mg daily dose of FT-4202, a potential disease-modifying oral treatment for sickle cell disease (SCD), was well-tolerated and safe, and improved several measures of red blood cell health after 14 days of treatment, according to recent data from an ongoing Phase 1 trial.
06 Apr 2021
Global Blood Therapeutics (GBT) has been granted exclusive global rights to two small-molecule research programs for sickle cell disease (SCD) as part of a newly announced agreement between GBT and Sanofi.
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