Hundreds of clinical trials are rolled out around the world monthly, and many of them are designed to specifically uncover and manage the medical needs of people with sickle cell disease and trait. We keep an updated list of these global studies here, so you don’t have to go searching for them. There might be active study recruitment and enrollment happening at a site near you. Explore the list below to see the different types of studies, and use the navigation options on the left to get as specific as you would like.
Sickle cell anemia (SCA) is one of the most neglected diseases worldwide, according to the World Health Organization.
1 Brazil site
18 to 60 Years
N/A
The purpose of this study is to compare the efficacy and safety of 2 doses of crizanlizumab (5.
9 Brazil sites
9 United States sites
6 United Kingdom sites
5 Italy sites
5 Belgium sites
5 Germany sites
4 Spain sites
3 Netherlands sites
3 India sites
3 Greece sites
3 Colombia sites
3 France sites
2 Turkey sites
2 Canada sites
2 Panama sites
2 Lebanon sites
1 South Africa site
1 Jordan site
1 Ghana site
1 Finland site
1 Oman site
> 12 Years
Phase 3
The goal of the study is to compare the efficacy and safety of crizanlizumab + standard of care to standard of care alone on renal function in sickle cell disease patients ≥ 16 years with chronic kidney disease due to sickle cell nephropathy.
6 United States sites
5 Brazil sites
3 Italy sites
3 Spain sites
3 Turkey sites
2 France sites
2 Greece sites
2 United Kingdom sites
1 South Africa site
1 Netherlands site
> 16 Years
HbSS
Phase 2
The purpose of the Phase 2 CSEG101B2201 study is to confirm and to establish appropriate dosing and to evaluate the safety in pediatric participants ages 6 months to <18 years with a history of VOC with or without HU/HC, receiving crizanlizumab for 2 years.
19 United States sites
5 Spain sites
4 Belgium sites
3 Brazil sites
3 Colombia sites
3 India sites
3 Italy sites
2 Canada sites
2 Germany sites
2 Lebanon sites
2 Turkey sites
2 United Kingdom sites
1 Oman site
1 Switzerland site
1 France site
6 to 17 Years
HbSS, HbSC
Phase 2
Stroke is a frequent complication of sickle cell disease (SCD), with varying levels of central nervous system (CNS) involvement.
1 Brazil site
> 35 Years
Phase 1/Phase 2
This study will investigate the safety, tolerability and potential for the use of up to three daily doses of 30-40 mg/kg HU (daily) upon hospitalization for painful vaso-occlusive crises .
1 Brazil site
18 to 60 Years
HbSS
Phase 2
So far, no study investigated the safety and efficacy analgesic of transcranial direct current stimulation (tDCS) associated to peripheral electrical stimulation (PES) in individuals with SCD who suffer from chronic pain.
1 Brazil site
18 to 50 Years
Phase 2
This research is being done so that we can look at the safety and efficacy of deferiprone in people with sickle cell disease or other anemias.
9 United States sites
8 Egypt sites
5 Brazil sites
4 United Kingdom sites
3 Saudi Arabia sites
3 Tunisia sites
3 Turkey sites
1 Canada site
1 Qatar site
> 2 Years
Phase 4
