Clinical Trials

Hundreds of clinical trials are rolled out around the world monthly, and many of them are designed to specifically uncover and manage the medical needs of people with sickle cell disease and trait. We keep an updated list of these global studies here, so you don’t have to go searching for them. There might be active study recruitment and enrollment happening at a site near you. Explore the list below to see the different types of studies, and use the navigation options on the left to get as specific as you would like.

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Hydroxyurea Therapy for Neurological and Cognitive Protection in Pediatric Sickle Cell Anemia in Uganda: A Single Arm Open Label Trial, “BRAIN SAFE II”

Worldwide, an estimated 200,000 babies are born with Sickle Cell Anemia (SCA) annually.

Locations

1 Uganda site

Age

3 to 9 Years

Genotypes

HbSS

Phase

Phase 3

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Preventing Stroke Triggers in Children With Sickle Cell Anaemia in Mulago Hospital, Kampala (PREST ): a Randomized Control Trial

Sickle cell anaemia (SCA) is a common hereditary haemoglobin disorder in Africa.

Locations

1 Uganda site

Age

2 to 12 Years

Phase

Phase 2/Phase 3

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Realizing Effectiveness Across Continents With Hydroxyurea (REACH): A Phase I/II Pilot Study Of Hydroxyurea For Children With Sickle Cell Anemia

REACH is a prospective, phase I/II open-label dose escalation trial of hydroxyurea for children with confirmed SCA between 12 months and 10 years of age.

Locations

1 Angola site

1 Kenya site

1 Congo, The Democratic Republic of the site

1 Uganda site

Age

1 to 10 Years

Genotypes

HbSS

Phase

Phase 1/Phase 2

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