Hundreds of clinical trials are rolled out around the world monthly, and many of them are designed to specifically uncover and manage the medical needs of people with sickle cell disease and trait. We keep an updated list of these global studies here, so you don’t have to go searching for them. There might be active study recruitment and enrollment happening at a site near you. Explore the list below to see the different types of studies, and use the navigation options on the left to get as specific as you would like.
This study examines how well a new, potential medicine called NDec works and is tolerated in people with sickle cell disease.
398 United States sites
155 India sites
125 United Kingdom sites
75 Canada sites
75 Italy sites
50 France sites
50 Spain sites
50 Turkey sites
49 Greece sites
25 South Africa sites
4 Switzerland sites
> 18 Years
Phase 2
The purpose of this study is to evaluate the safety, tolerability, efficacy, pharmacokinetics and pharmacodynamics of GBT021601.
105 United States sites
9 Nigeria sites
3 Kenya sites
6 Months - 65 Years
Phase 2/Phase 3
This study is designed to evaluate the efficacy, safety and pharmacokinetics of crovalimab compared with placebo as adjunct therapy in the prevention of VOEs in participants with SCD.
153 Brazil sites
120 Turkey sites
77 Spain sites
72 United States sites
72 Italy sites
48 France sites
19 United Kingdom sites
12 Years - 55 Years
Phase 2
This registry is an observational study designed to evaluate the effect of Oxbryta in individuals with SCD in a real-world setting.
The purpose of this study is to evaluate the efficacy, safety and tolerability of treatment with EDIT-301 in adult participants with severe sickle cell disease (SCD).
424 United States sites
75 Canada sites
18 Years - 50 Years
Phase 1/Phase 2
This study aims to enroll 58 pre-adolescent (<13 years) pediatric participants with sickle cell disease (SCD) who have a pre-adolescent sibling bone marrow donor.