Clinical Trial Finder

Hundreds of clinical trials are rolled out around the world monthly, and many of them are designed to specifically uncover and manage the medical needs of people with sickle cell disease and trait. We keep an updated list of these global studies here, so you don’t have to go searching for them. There might be active study recruitment and enrollment happening at a site near you. Explore the list below to see the different types of studies, and use the navigation options on the left to get as specific as you would like.

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A Multicentre Trial Evaluating the Efficacy and Safety of Oral Decitabine Tetrahydrouridine (NDec) in Patients With Sickle Cell Disease

This study examines how well a new, potential medicine called NDec works and is tolerated in people with sickle cell disease.

Locations

1838 United States sites

1239 India sites

492 United Kingdom sites

365 Canada sites

358 Italy sites

296 Turkey sites

262 Greece sites

201 France site

197 Spain sites

98 South Africa sites

43 Lebanon sites

4 Switzerland sites

3 Oman sites

Age

> 18 Years

Phase

Phase 2

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ESCORT-HU Extension: European Sickle Cell Disease Cohort – Hydroxyurea – Extension

As safety information pertaining to the long-term use of HU remains incomplete in spite of the first safety study (ESCORT-HU), an extension of the latter is proposed.

Locations

5589 France sites

422 Germany sites

338 Italy sites

335 French Guiana sites

171 Martinique site

169 Guadeloupe sites

83 Greece sites

61 Réunion site

Age

> 2 Years

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An Adaptive, Randomized, Placebo-controlled, Double-blind, Multi-center Study of Oral Etavopivat, a Pyruvate Kinase Activator in Patients With Sickle Cell Disease (HIBISCUS)

This clinical trial is a Phase 2/3 study that will evaluate the efficacy and safety of etavopivat and test how well etavopivat works compared to placebo to improve the amount of hemoglobin in the blood and to reduce the number of vaso-occlusive crises (times when the blood vessels become blocked and cause pain).

Locations

4406 United States sites

591 United Kingdom site

415 Spain sites

414 France sites

331 Italy site

329 Greece sites

249 Canada sites

170 Oman sites

166 Germany sites

165 Lebanon sites

Age

12 Years - 65 Years

Phase

Phase 2/Phase 3

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