Hundreds of clinical trials are rolled out around the world monthly, and many of them are designed to specifically uncover and manage the medical needs of people with sickle cell disease and trait. We keep an updated list of these global studies here, so you don’t have to go searching for them. There might be active study recruitment and enrollment happening at a site near you. Explore the list below to see the different types of studies, and use the navigation options on the left to get as specific as you would like.
One in 300 Jamaicans have HbSS sickle cell disease, and of these, up to 70% will suffer from sickle cell leg ulcers (SCLUs).
1 Jamaica site
13 to 70 Years
HbSS
N/A
Pain is the most common component of the morbidity seen in sickle cell disease (SCD), and may be acute or chronic.
1 Jamaica site
> 14 Years
An open label, safety and pharmacokinetic study of oral hydroxyurea solution administered to children from 6 months to 17.
5 United Kingdom sites
1 Jamaica site
6 to 17 Years
HbSS
Phase 2
The primary goal of the Phase II EXTEND trial is to investigate the effects of open-label hydroxyurea treatment, escalated to maximum tolerated dose, for children with Sickle Cell Anemia and either conditional (170 - 199 cm/sec) or abnormal (≥200 cm/sec) Transcranial Doppler velocities.
1 Jamaica site
2 to 17 Years
HbSS
Phase 2
The purpose of this Phase 1/2 study is to determine the feasibility and safety of stem cell collection and gamma-globin gene transfer, and success of gene correction in subjects with sickle cell disease .
4 United States sites
1 Jamaica site
18 to 45 Years
Phase 1/Phase 2
The purpose of this study is to determine whether enalapril or antioxidant therapy (N-Acetylcysteine) is effective in reducing microalbuminuria in children with sickle cell disease and and its progression to sickle nephropathy .
1 Jamaica site
2 to 18 Years
N/A
