Hundreds of clinical trials are rolled out around the world monthly, and many of them are designed to specifically uncover and manage the medical needs of people with sickle cell disease and trait. We keep an updated list of these global studies here, so you don’t have to go searching for them. There might be active study recruitment and enrollment happening at a site near you. Explore the list below to see the different types of studies, and use the navigation options on the left to get as specific as you would like.
Background: Sickle cell disease (SCD) is an inherited hemoglobin disorder.
1 United States site
18 to 70 Years
SS, SC
Phase 2
Background: Venous thromboembolism (VTE) includes the abnormal clotting of blood in a deep vein of the upper or lower limbs (deep vein thrombosis) that may travel to and block a blood vessel in the lung (pulmonary embolism).
1 United States site
18 to 80 Years
HbSS, HbSC
A Study to Evaluate the Safety and Efficacy of IMR-687 in Subjects with Sickle Cell Disease .
10 United States sites
4 Tunisia sites
3 Lebanon sites
1 Greece site
1 Italy site
1 Netherlands site
1 Oman site
18 to 65 Years
HbSS
Phase 2
Background: Sickle cell disease (SCD) is a disorder that causes episodes of acute pain and progressive organ damage.
1 United States site
18 to 70 Years
Phase 1/Phase 2
Background: Sickle cell disease (SCD) is a chronic illness.
1 United States site
> 18 Years
Background: Sickle cell disease (SCD) is an inherited blood disorder.
1 United States site
18 to 99 Years
HbSS
Early Phase 1
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and efficacy of SHP655 in participants with baseline health sickle cell disease (SCD) and SCD with acute vaso-occlusive crisis (VOC).
14 United States sites
18 to 65 Years
HbSS
Phase 1/Phase 2
The purpose of this study is to determine if a search strategy of searching for an HLA-matched unrelated donor for allogeneic transplantation if possible then an alternative donor if an HLA-matched unrelated donor is not available versus proceeding directly to an alternative donor transplant will result in better survival for allogeneic transplant recipients within 2 years after study enrollment.
43 United States sites
N/A
Background: Sickle cell disease is a common inherited blood disorder.
1 United States site
18 to 99 Years
SS
The purpose of this research study is to compare two different ways to give opioid pain medicine to treat sickle cell disease pain that is bad enough to go to the emergency department for treatment.
6 United States sites
> 18 Years
SS, SC
Phase 3
