Hundreds of clinical trials are rolled out around the world monthly, and many of them are designed to specifically uncover and manage the medical needs of people with sickle cell disease and trait. We keep an updated list of these global studies here, so you don’t have to go searching for them. There might be active study recruitment and enrollment happening at a site near you. Explore the list below to see the different types of studies, and use the navigation options on the left to get as specific as you would like.
Children with sickle cell disease systematically receive a transfusion 2 to 5 days before scheduled surgery (with the exception of minor surgeries) in order to avoid post-operative complications of which the vaso-occlusive crisis and acute thoracic syndrome are the most frequent.
1 Belgium site
< 18 Years
The purpose of this study is to compare the efficacy and safety of 2 doses of crizanlizumab (5.
9 Brazil sites
9 United States sites
6 United Kingdom sites
5 Italy sites
5 Belgium sites
5 Germany sites
4 Spain sites
3 Netherlands sites
3 India sites
3 Greece sites
3 Colombia sites
3 France sites
2 Turkey sites
2 Canada sites
2 Panama sites
2 Lebanon sites
1 South Africa site
1 Jordan site
1 Ghana site
1 Finland site
1 Oman site
> 12 Years
Phase 3
The purpose of the Phase 2 CSEG101B2201 study is to confirm and to establish appropriate dosing and to evaluate the safety in pediatric participants ages 6 months to <18 years with a history of VOC with or without HU/HC, receiving crizanlizumab for 2 years.
19 United States sites
5 Spain sites
4 Belgium sites
3 Brazil sites
3 Colombia sites
3 India sites
3 Italy sites
2 Canada sites
2 Germany sites
2 Lebanon sites
2 Turkey sites
2 United Kingdom sites
1 Oman site
1 Switzerland site
1 France site
6 to 17 Years
HbSS, HbSC
Phase 2
Sickle cell disease is associated with significant morbi-mortality hence the interest in an early and targeted care.
3 Belgium sites
> 6 Years
SS, SC
N/A
This is a single-arm, open-label, multi-site, single-dose Phase 1/2 study in subjects with severe sickle cell disease (SCD).
8 United States sites
1 Belgium site
1 Canada site
1 Germany site
1 Italy site
1 United Kingdom site
12 to 35 Years
Phase 1/Phase 2
The objective of the study is to refine our knowledge on the physiopathology of the symptoms and the complications for the patients affected by a drepanocytic syndrome.
1 Belgium site
> 17 Years