Hundreds of clinical trials are rolled out around the world monthly, and many of them are designed to specifically uncover and manage the medical needs of people with sickle cell disease and trait. We keep an updated list of these global studies here, so you don’t have to go searching for them. There might be active study recruitment and enrollment happening at a site near you. Explore the list below to see the different types of studies, and use the navigation options on the left to get as specific as you would like.
The investigators will attempt to develop a more accurate equation to estimate eGFR in pediatric and adult sickle cell patients .
4 United States sites
5 to 50 Years
SCA, HbSS
The goal of the study is to evaluate the efficacy and safety of crizanlizumab in SCD patients with priapism.
17 United States sites
> 16 Years
HbSS, HbSC
Phase 2
This study is a Phase 3, randomized, double-blind, placebo-controlled study of voxelotor in pediatric participants, aged ≥ 2 to < 15 years old, with Sickle Cell Disease.
17 United States sites
5 Nigeria sites
4 Egypt sites
4 United Kingdom sites
3 Italy sites
3 Kenya sites
2 Ghana sites
2 Oman sites
2 Saudi Arabia sites
1 France site
2 to 14 Years
SCA
Phase 3
The ASCENT Trial is a single arm, multi-center, phase II study.
7 United States sites
< 20 Years
Phase 2
The SCD-CARRE trial is a Phase 3, prospective, randomized, multicenter, controlled, parallel two-arm study aimed to determine if automated exchange blood transfusion and standard of care administered to high mortality risk adult SCD patients reduces the total number of episodes of clinical worsening of SCD requiring acute health care encounters (non-elective infusion center/ER/hospital visits) or resulting in death over 12 months as compared with standard of care.
16 United States sites
> 18 Years
Phase 3
The purpose of this study is to assess the potential interventions of exercises in adults with sickle cell anemia (SCA) and cardiopulmonary disease; only including the more severe genotypes of sickle cell disease.
1 United States site
> 18 Years
N/A
Approximately 60 subjects will be enrolled into this double-blind, placebo-controlled study for the Deferoxamine Intradermal Delivery Patch (DIDP).
4 United States sites
> 18 Years
Phase 1/Phase 2
The goal of the study is to compare the efficacy and safety of crizanlizumab + standard of care to standard of care alone on renal function in sickle cell disease patients ≥ 16 years with chronic kidney disease due to sickle cell nephropathy.
9 United States sites
5 Brazil sites
4 Spain sites
3 Italy sites
3 Turkey sites
3 United Kingdom sites
2 France sites
2 Greece sites
2 South Africa sites
1 Netherlands site
1 Lebanon site
1 Panama site
> 16 Years
HbSS
Phase 2
SHP655 is a medicine used to treat sickle cell disease (SCD).
14 United States sites
18 to 65 Years
HbSS
Phase 1
This multi-center study will compare the effectiveness of adding virtual peer mentoring (PM) to a structured education-based (STE) transition program for emerging adults with sickle cell disease to determine its effect on decreasing the number of acute care visits per year, improving patient-reported outcomes, and reducing healthcare utilization among emerging adults with sickle cell disease (EA-SCD) .
14 United States sites
> 16 Years
N/A
