Clinical Trial Finder

Hundreds of clinical trials are rolled out around the world monthly, and many of them are designed to specifically uncover and manage the medical needs of people with sickle cell disease and trait. We keep an updated list of these global studies here, so you don’t have to go searching for them. There might be active study recruitment and enrollment happening at a site near you. Explore the list below to see the different types of studies, and use the navigation options on the left to get as specific as you would like.

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A Phase II Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease

The study is a Phase II clinical trial.

Locations

94 United States sites

Age

16 Years - 60 Years

Phase

Phase 2

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Pain Management of Vaso-Occlusive Crisis in Children and Young Adults With Sickle Cell Disease-Effect of Virtual Reality Technology

Acute vaso-occlusive crisis (VOC) is the most common complication in patients with sickle cell disease (SCD) and pain related to VOC is often inadequately treated.

Locations

176 United States sites

Age

6 Years - 25 Years

Phase

Not Applicable

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Hyperbaric Oxygen Therapy in Sickle Cell Pain

Hyperbaric oxygen therapy in acute sickle cell pain crisis.

Locations

80 United States sites

Age

> 19 Years

Phase

Not Applicable

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A Phase II Pilot Study of Nonmyeloablative Conditioning Hematopoietic Stem Cell Transplantation in Children With Sickle Cell Disease Who Have a Matched Related Major ABO-Incompatible Donor (Sickle-AID)

The aim of this study to evaluate the safety and efficacy of a nonmyeloablative conditioning regimen for allogeneic hematopoietic stem cell transplantation (HSCT) in pediatric patients with sickle cell disease (SCD) who have a matched related major ABO-incompatible donor.

Locations

107 Canada sites

Age

1 Year - 19 Years

Phase

Phase 2

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The Epidemiology of Silent and Overt Strokes in Adults With Sickle Cell Disease: a Prospective Cohort Study

Sickle Cell Disease (SCD) is a rare disease occurring in an estimated 100,000 individuals, often poor and underserved, in the US.

Locations

1376 United States sites

Age

> 18 Years

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Register Sichelzellkrankheit Der GPOH

Sickle cell disease is one of the most common hereditary diseases.

Locations

90 Germany sites

Age

0 Years - 100 Years

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Investigation of the Genetics of Hematologic Diseases

The purpose of this study is to collect and store samples and health information for current and future research to learn more about the causes and treatment of blood diseases.

Locations

84 United States sites

Age

Years

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Measures of Respiratory Health

The Lung Clearance Index, measured by multiple breath washout, is a measure of lung function that is considered a research tool in Canada as the device used to measure it is not approved by Health Canada.

Locations

99 Canada sites

Age

30 Months - 30 Years

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Safety and Efficacy of Prophylactic Defibrotide in Children, Adolescents, and Young Adults With Sickle Cell Disease or Beta Thalassemia Following MAC and Haploidentical Stem Cell Transplantation Utilizing CD34 Enrichment and T-Cell (CD3) Addback

This is a follow-up trial to NYMC 526 (NCT01461837) to assess the safety, efficacy and toxicity of administering Defibrotide prophylaxis for high-risk sickle cell or beta thalassemia patients undergoing a familial haploidentical allogeneic stem cell transplantation with CD34 enrichment and T-cell addback.

Locations

328 United States sites

Age

6 Months - 34 Years

Phase

Phase 2

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Sickle Cell Disease (SCD) Biochip’: Towards a Simple and Reliable Way to Monitor Sickle Cell Disease

'Sickle-shaped' anemia was first clinically described in the US in 1910, and the mutated heritable sickle hemoglobin molecule was identified in 1949.

Locations

88 United States sites

Age

> 12 Years

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